research axis 3 Archives - Page 3 of 3

13 Oct 2017

Daniel J. Bernard, PhD

13 Oct 2017

Address

514 398-2525
daniel.bernard@mcgill.ca
http://www.mcgill.ca/bernardlab/
Pharmacology & Therapeutics
McGill University
McIntyre Medical Sciences Building
3655, Promenade Sir-William-Osler,
Local 1315A
Montreal, QC H3G 1Y7

Fax: 514 398-2045
Labo: 514 398-1664

Research interests

Transcriptional regulation of follicle-stimulating hormone synthesis
Mechanisms of GnRH action
Molecular mechanisms of IGSF1-deficiency syndrome

The Bernard’s lab investigates molecular mechanisms of pituitary hormone synthesis using in vitro and in vivo approaches.

Research in the lab concerns:

1) signal transduction mechanisms through which members of the transforming growth factor β superfamily regulate pituitary follicle-stimulating hormone (FSH) synthesis,

2) mechanisms of gonadotropin-releasing hormone (GnRH) signaling in pituitary gonadotrope cells.

3) hypothalamic-pituitary control of thyroid hormone production.

Members of the laboratory

Evan Buddle, BSc
Master student
evan.buddle@mail.mcgill.ca

Hailey Schultz, MSc
PhD student
Hailey.scultz@mail.mcgill.ca

Mary Loka, BSc
PhD student
mary.loka@mail.mcgill.ca

Yangfan Jin, BSc
PhD student
yangfan.jin@mail.mcgill.ca

Yeu-Farn (Claire) Lin, MSc
PhD student
Yeu-farn.lin@mail.mcgill.ca

Luisina Ongaro, PhD
Research associate
luisina.ongarogambino@mcgill.ca

Xiang Zhou, MSc
Laboratory technician
xiang.zhou3@mcgill.ca

Ying Wang, BSc
Laboratory technician
ying.wang5@mcgill.ca

Publications

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13 Oct 2017

Eric Asselin, PhD

13 Oct 2017

Address

819 376-5011 Ext. 3317
eric.asselin@uqtr.ca
www.asselinlab.com
3351, boul. des Forges, C.P. 500
Trois-Rivières, QC G9A 5H7

Research interests

Uterine and ovarian biology, physiology and endocrinology
Hormone-dependent cancers of the female reproductive system
Animal models and transgenesis

Dr. Asselin’s research laboratory is interested understanding the regulation of cell survival and cell death in the context of embryo implantation, endometrial decidualization and in pathological conditions such as chemoresistance in gynecological cancers (endometrial and ovarian). More precisely, his laboratory has been actively investigating the PI-3K/Akt pathway in this context. Animal models, transgenic mouse human biopsies, cell lines are used in his laboratory to study this signaling pathway at the cellular and molecular level. His laboratory include 1 research professional, 1 postdoctoral fellow, 3 PhD students and 2 MSc students. For the last 16 years, he has trained more than 75 undergraduate and graduate students and postdoctoral fellows. His group has published more than 92 publications in peer-review international scientific journals, with a citation impact factor of 37 (H factor). He was recipient of a FRQS chercheur-boursier, a CIHR New Investigator Award and the Canada Research Chair in Molecular Gyneco-oncology from 2006 to 2016.

Members of the laboratory

Francois Fabi, MSc
PhD student
francois.fabi@uqtr.ca

Pascal Adam, MSc
PhD student
pascal.adam@uqtr.ca

Laurence Tardif, BSc
PhD student
laurence.tardif@uqtr.ca

Muhammad Nadeem Asghar, PhD
Postdoc
Muhammad.Nadeem.Asghar2@uqtr.ca

Dadou LOKENGO LIKONZA MD / Gynécologue-Obstétricien
PhD student
dadoulokengo@yahoo.fr

Junie Chansi, MSc
PhD student
junye3@gmail.com

Sophie Parent, MSc
Research assistant
sophie.parent@uqtr.ca

Publications

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11 Jun 2016

Derek Boerboom, DVM, PhD

11 Jun 2016

Address

450 773-8521 Ext. 0160
derek.boerboom@umontreal.ca
http://www.apps.medvet.umontreal.ca/crrf/en/team-members/derek-boerboom-dmv-ph-d/
Université de Montréal
Département de biomédecine vétérinaire
3200, Sicotte, St-Hyacinthe, QC J2S 2M2

Fax: 450 778-8103

Research interests

Roles of developmental signaling pathways in gonadal physiology
Cancers of the reproductive system
Transgenesis and functional genomics

Our primary field of interest is the role played by developmental signaling pathways in the functioning of the ovary. Pathways such as Wnt, Hippo and Slit/Robo are best known for their critical roles in a variety of tissues and cell types during embryonic development. It has become apparent, however, that these “developmental” pathways are also active in adult life, and their roles in this context are only beginning to become known. Using a functional genomics approach, our group has shown that the Wnt pathway is a key player in the ovary, acting downstream of the gonadotropins to regulate follicle survival, growth and ovulation. Current research projects are also examining the role of Hippo signaling in ovary and testis, as well as in the development of different cancers of the reproductive system, including the ovary, uterus and mammary gland.

Members of the laboratory

Florine Grudet, BSc
PhD student
florine.grudet@umontreal.ca

Michael Bérubé
DVM/PhD student
michael.berube@umontreal.ca

Francis Marien-Bourgeois
Lab technician
francis.marien-bourgeois@umontreal.ca

Publications

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