My researches focus on the genetic and physiologic determinism of the reproductive function in small ruminants. Concerning the genetic determinism, thanks to whole genome approaches (SNP chip genotyping, GWAS, high throughput DNA and RNA sequencing), we try to evidence causal mutations and cellular mechanisms controlling fertility associated traits in male and female sheep and goat (sperm parameters, ovarian follicle reserve, ovulation rate, litter size, embryonic lethality). From the physiology point of view, we try to associate the endocrine and intra ovarian hormonal profile changes with genetic variations affecting puberty, fertility and prolificacy in ewes.